| 产品英文名称 | Human SPOCK1 Protein（His Tag） |
| 产品中文名称 | 重组人SPOCK1蛋白 |
| 别名 | SPOCK Protein, Human; TESTICAN Protein, Human; testican-1 Protein, Human; TIC1 Protein, Human; TICN1 Protein, Human |
| 种属 | 人 |
| 序列 | A DNA sequence encoding the human SPOCK1 (Q08629) ( Met 1-Trp439) was expressed with a C-terminal polyhistidine tag. |
| 活性 | Testing in progress |
| 蛋白长度 | The secreted recombinant human SPOCK1 consists of 429 amino acids and predicts a molecular mass of 48.46 KDa. The apparent molecular mass of the protein is approximately 53 KDa in SDS-PAGE under reducing conditions due to glycosylation. |
| 纯度 | > 85% ，使用SDS-PAGE检测 |
| 特点&优势 | 采用 LAL 法检测，每 1 μg 蛋白质中的 EU 含量小于 1.0。 |
| 产品形式 | Lyophilized from sterile 20mM Tris, 500mM NaCl, 10% glycerol, pH 7.4. |
| 基因ID | 6695 |
| 蛋白序列链接 | https://www.uniprot.org/uniprotkb/Q08629/entry |
| 使用中注意事项 | 开盖使用前，请先离心。本产品为冻干粉，推荐用该产品配套的Reconstitution Buffer进行复溶，且浓度不低于100 µg/mL。客户可根据后续的实验需求，进行进一步的稀释。 |
| 保存建议 | 本产品为冻干粉形式，建议将产品保存于-20℃以下的干燥环境中。本产品溶解之后，可在4℃保存2-7天，长期使用请置于-20℃以下。为长期保存，推荐添加载体蛋白（0.1% HSA或者BSA），并酌情分装保存，避免反复冻融。 |
| 运输条件 | 冰袋运输（蓝冰） |
| 警告 | 本文列出的产品仅供研究使用，不适用于人类或临床诊断。我们产品所推荐应用，不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为，我们不承担任何责任。 |
| 背景 | Osteonectin, also known as SPOCK1, is an extracellular heparan/chondroitin sulfate proteoglycan. Members of this family are known as testicans, also called SPOCKs. They are characterized structurally by an N-terminal testican-specific domain, a follistatin-like region, a calcium-binding domain, a thyroglobulin-like domain, and an acidic C-terminal domain with two putative glycosaminoglycan attachment sites. SPOCKs are enriched in brain and have been shown to regulate neuronal attachment and outgrowth. They contain inhibitory regions in several domains targeted to different classes of protease, and in some cases may act as protease inhibitors. Osteonectin contains 1 Kazal-like domain and 1 thyroglobulin type-1 domain. Up to now, little is known about osteonectin’s function. It may play a role in cell-cell and cell-matrix interactions. Osteonectin also may contribute to various neuronal mechanisms in the central nervous system. |
Fig.重组人SPOCK1蛋白
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