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Fig.KTB1100 - CheKine™ 乳酸检测试剂盒（微量法）

• 怎么设置样本对照组

  只需要Lactate Dehydrogenase用Lactate Assay Buffer替代就行。Working Reagent：每孔准备 55 µL 工作液，现配现用：吸取 41 µL Lactate Assay Buffer，8 µL Lactate Dehydrogenase Cofactor, 5 µL WST-8, 1 µL Enhancer ，混合均匀。

• 你好 我想测细胞培养基的乳酸含量 请问培养基的颜色以及ph值会对检测结果有影响吗？

  经测试，该试剂盒可以用于检测细胞培养基中乳酸的含量，培养基颜色以及pH对检测结果没有影响。

本产品已在(75)种出版物中被引用

• “All-in-one” metal polyphenol network nanocapsules integrated microneedle patches for lipophagy fueled ferroptosis-mediated multimodal therapy

  作者：王文浩 杂志名称：Respiratory Research IF：10

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• α-myosin heavy chain lactylation maintains sarcomeric structure and function and alleviates the development of heart failure

  作者：N Zhang, Y Zhang, J Xu, P Wang, B Wu, S Lu, X Lu, ... 杂志名称：Scientific Reports  IF：26

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• Revealing the effects of lactate on bovine SCNT embryo development through transcriptome sequencing analyses.

  作者：Li, Nannan, et al. 杂志名称：Theriogenology IF：2

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• A Novel Prognostic Signature Integrating Immune and Glycolytic Pathways for Enhanced Prognosis and Immunotherapy Prediction in Hepatocellular Carcinoma.

  作者：Zhang, Zeyu, et al. 杂志名称： Journal of Hepatocellular Carcinoma  IF：3

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• Gingerenone A inhibits LDHA-mediated glycolysis and restores sunitinib sensitivity in renal cell carcinoma

  作者：Z Chen, Y Zhang, L Ma, Y Song, W Li, Z Sun, ... 杂志名称：Research Square IF：6

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• Kindlin-2 enhances c-Myc translation through association with DDX3X to promote pancreatic ductal adenocarcinoma progression

  作者：C Liu, K Jiang, Y Ding, A Yang, R Cai, P Bai, ... 杂志名称：Molecular medicine reports IF：13

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• Glycolysis regulates palatal mesenchyme proliferation through Pten-Glut1 axis via Pten classical and non-classical pathways.

  作者：Wang, Yijia, et al. 杂志名称： Cell Biology and Toxicology  IF：6

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• Baicalin promotes anti-tumor immunity in hepatocellular carcinoma through HIF-1α/Lactate/CXCL9 axis.

  作者：Yang, Xuemei, et al. 杂志名称：Biochemical Pharmacology  IF：6

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• Gastrodin regulates H3K14la through the CDT2-KAT2A axis to treat Sepsis-induced myocardial dysfunction.

  作者：Yu, Huiming, et al. 杂志名称：International Immunopharmacology  IF：5

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• Natural product fargesin interferes with H3 histone lactylation via targeting PKM2 to inhibit non‐small cell lung cancer tumorigenesis.

  作者：Guo, Zizhang, et al. 杂志名称：BioFactors IF：5

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• LRRN3 protects dopaminergic neurons by inhibiting glycolysis in Parkinson's disease

  作者：J Gao, K Qin, W Xian, J Ren, A Xie, B Hou 杂志名称：Cytotherapy  IF：3

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• Leveraging AI technology for distinguishing Eucommiae Cortex processing levels and evaluating anti-fatigue potential.

  作者：Pan, Yijing, et al. 杂志名称：Computers in Biology and Medicine  IF：6

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• High Sugar Induced RCC2 Lactylation Drives Breast Cancer Tumorigenicity Through Upregulating MAD2L1.

  作者：Zheng, Bowen, et al. 杂志名称： Advanced Science  IF：14

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• Divalent metal ions enhance bone regeneration through modulation of nervous systems and metabolic pathways.

  作者：Luo, Ying, et al. 杂志名称： Bioactive Materials IF：20

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• KAT7 enhances the proliferation and metastasis of head and neck squamous carcinoma by promoting the acetylation level of LDHA.

  作者：Lu, Ying, et al. 杂志名称：Cancer Letters IF：9

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• Human papillomavirus-16 E6 activates the pentose phosphate pathway to promote cervical cancer cell proliferation by inhibiting G6PD lactylation

  作者：孟庆飞 杂志名称：Neuroscience IF：12

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• Oncogenic HPV-induced high expression of ESM1 predicts poor prognosis and regulates aerobic glycolysis in cervical cancer."

  作者：Yuan, Lin, et al. 杂志名称：Iscience IF：5

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• Enhancing photocatalytic hydrogen production from engineered Escherichia coli-biohybrid system via intracellular electron redirection.

  作者：Lin, Song, et al. 杂志名称：Chemical Engineering Journal IF：13

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• Microcystin-LR disrupts ovarian granulosa cell glycolysis via GSK3β-Mediated HK2 mitochondrial dissociation: Evidence from integrated In Vivo and In Vitro models

  作者：J Yuan, X Li, S Yan, C Luo, S Xian, Y Li, J Wu 杂志名称：JOURNAL OF BIOLOGICAL CHEMISTRY IF：3

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• Blocking ubiquitination of hnRNPA1 maintains the self-renewal of breast cancer stem cells via mutually exclusive splicing of PKM pre-mRNA

  作者：M He, X Lv, H Li, WW Tong, Y Yan, X Sun, S Zhou, ... 杂志名称：J Agric Food Chem IF：

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• Exosomes from cisplatin-induced dormant cancer cells facilitate the formation of premetastatic niche in bone marrow through activating glycolysis of BMSCs

  作者：J Xu, X Feng, N Yin, L Wang, Y Xie, Y Gao, ... 杂志名称：ACS Nano IF：3

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• Histone H3K18 lactylation-dependent epigenetic activation of RUNX2 orchestrates PI3K/AKT oncogenic signaling in laryngeal squamous cell carcinoma

  作者：D Fu, X Huang, Y Lin, F Yu, H Wu 杂志名称： IF：2

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• The potential role of CMC1 as an immunometabolic checkpoint in T cell immunity.

  作者：Chen, Yuwen, et al. 杂志名称：Oncoimmunology IF：6

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• Mitophagy Reprograms Lactate Metabolism to Suppress THBS1 via H3K18la Reduction, Alleviating Intervertebral Disc Degeneration

  作者：K Wang, X Wu, H Li, X Xu, F Cheng, J Chen, H Zhou, ... 杂志名称：International Journal of Molecular Medicine IF：11

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• Targeting the HSP60/p53 Axis with Extracellular Vesicle-Delivered siRNA Reprograms Glycolysis in Prostate Cancer

  作者：Meng-Yao Xu （徐梦瑶) 杂志名称：Biochim Biophys Acta IF：10

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• dsHMGB1, released from IL-17A-induced pyroptotic prostate epithelial cells, drives M1 polarization by promoting Pfkp-mediated glycolysis via Jak2/Stat1 …

  作者：W Ma, Y Zhang, W Xu, Y Hu, W Wu, ... 杂志名称： IF：10

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• DLGAP5 enhances bladder cancer chemoresistance by regulating glycolysis through MYC stabilization.

  作者：Deng, Zhao, et al. 杂志名称：Theranostics IF：13

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• Jaceosidin Attenuates Sepsis-Induced Myocardial Dysfunction by Promoting SIRT2-Mediated Inhibition of Histone H3K18 Lactylation

  作者：H Yu, M Liu, S Hou, J Wu, Q Du, F Feng, S Wang, ... 杂志名称：Cell death discovery IF：5

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• Targeting ALDOA to modulate tumorigenesis and energy metabolism in retinoblastoma.

  作者：Wang, Yinghao, et al. 杂志名称：Iscience IF：5

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• Transcription Factor STAT3-Activated LDHB Promotes Tumor Properties of Endometrial Cancer Cells by Inducing MDH2 Expression.

  作者：Shen, Li, et al. 杂志名称： Molecular Biotechnology  IF：2

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• Via inhibiting glycolysis and oxidative respiration and promoting ferroptosis, ETFDH inhibits the proliferation of colorectal cancer.

  作者：Feng, Yaoyao, et al. 杂志名称： IF：

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• METTL14‐Mediated M6A Modification of LINC01094 Induces Glucose Metabolic Reprogramming in Breast Cancer by Recruiting the PKM2/JMJD5 Complex.

  作者：Wang, Mengqi, et al. 杂志名称：Advanced Science  IF：14

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• MRPL12 K163 acetylation inhibits ccRCC via driving mitochondrial metabolic reprogramming

  作者：X Ji, F Xue, Y Wang, D Gao, J Sun, T Dong, Q Mu, ... 杂志名称：Journal of Ethnopharmacology IF：10

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• IGF2BP1 stabilizes Akt2 mRNA to promote glucose metabolism and maintain spermatogonial proliferation.

  作者：Liu, Yanan, et al. 杂志名称： Reproduction  IF：4

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• Hypoxia Promotes the In Vitro Proliferation of Buffalo Spermatogonial Cells by Increasing Lactate and H3K18la Lactylation Levels.

  作者：Li, Mengqi, et al. 杂志名称：Cells 14.11 IF：

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• UGDH lactylation aggravates osteoarthritis by suppressing glycosaminoglycan synthesis and orchestrating nucleocytoplasmic transport to activate MAPK signaling.

  作者：Lan, Weiren, et al. 杂志名称： Advanced Science IF：14

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• Pump‐Free Unidirectional Vertical Centrifugal Microfluidic Platform for Dynamic 3D Tumor Cluster Culture and Functional Drug Screening

  作者：K Ning, Y Xie, X Yang, Y Chen, W Sun, ... 杂志名称：cancer science IF：10

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• Comprehensive bioinformatics analysis of the solute carrier family and preliminary exploration of SLC25A29 in lung adenocarcinoma

  作者：P Zheng, Z Mao, M Luo, L Zhou, L Wang, H Liu, ... 杂志名称： IF：6

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• Lactate exacerbates lung damage induced by nanomicroplastic through the gut microbiota–HIF1a/PTBP1 pathway

  作者：L Xuan, Z Xu, J Luo, Y Wang, Y Yan, C Qu, ... 杂志名称：Front Immunol IF：13

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• ZNF207-Driven PRDX1 Lactylation and NRF2 Activation in Regorafenib Resistance and Ferroptosis Evasion.

  作者：Yang, Tianfeng, et al. 杂志名称：Drug Resistance Updates IF：22

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• Targeting the PDK/PDH axis to reverse metabolic abnormalities by structure-based virtual screening with in vitro and in vivo experiments.

  作者：Yue, Jianda, et al. 杂志名称：International Journal of Biological Macromolecules IF：8

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• TAB182 regulates glycolytic metabolism by controlling LDHA transcription to impact tumor radiosensitivity.

  作者：Chen, Shi, et al. 杂志名称：Cell Death & Disease IF：8

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• Aspirin inhibited the Warburg effect induced by Ni-refining fumes via the Wnt/β-catenin pathway in Beas-2B cells

  作者：Y Gao, T Zhang, D Zhang, SY Wang, Y Wang, CP Yu, ... 杂志名称：Frontiers in Microbiology IF：

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• Neutrophil-derived heparin-binding protein increases endothelial permeability in acute lung injury by promoting TRIM21 and the ubiquitination of P65.

  作者：Zhang, Jian, et al. 杂志名称： Cell biology and toxicology  IF：6

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• IGF1R Enhances Calcium Oxalate Monohydrate-Induced Epithelial-Mesenchymal Transition by Reprogramming Metabolism via the JAK2/STAT3 Signaling.

  作者：Pan, Jiashan, et al. 杂志名称： International Journal of Biological Sciences IF：10

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• Regulatory effect of lactate on peripheral blood CD4+ T cell subsets in patients with rheumatoid arthritis.

  作者：Huang, Huina, et al. 杂志名称：Health Sciences IF：2

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• Dual activation of GCGR/GLP1R signaling ameliorates intestinal fibrosis via metabolic regulation of histone H3K9 lactylation in epithelial cells

  作者：Han Liu 杂志名称：Aquaculture Reports IF：15

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• Physical Encapsulation and Chemotherapy: A Synergistic Hydrogel Strategy for Tumor Suppression

  作者：宫雅杰 杂志名称：Environ Microbiol IF：10

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• CXCR4 regulates macrophage M1 polarization by altering glycolysis to promote prostate fibrosis.

  作者：Zhang, Yi, et al. 杂志名称：Cell Communication and Signaling IF：8

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• Vitamin C inhibits the growth of colorectal cancer cell HCT116 and reverses the glucose-induced oncogenic effect by downregulating the Warburg effect

  作者：C Yu, S Min, F Lv, L Ren, Y Yang, L Chen 杂志名称：FASEB JOURNAL, 17 Jan 2019 IF：4

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• Oral delivery of dextran-modified albumin nanoparticles loaded with shikonin for targeted therapy of colorectal cancer

  作者：Z Ren, J Zhao, S Li, Y Hong 杂志名称：BioRxiv IF：4

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• DANCR promotes septic cardiomyopathy by enhancing macrophage glycolytic reprogramming via the IGF2BP2/HK2 axis

  作者：C Ma, S Liu, Y Zhao, H Liu, X Zhang 杂志名称：Journal of Translational Medicine IF：4

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• Remote ischemic postconditioning-mediated neuroprotection against stroke by promoting ketone body-induced ferroptosis inhibition.

  作者：Huang, Lin-yan, et al. 杂志名称：ACS chemical neuroscience IF：4

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• SUMOylated GLUT1 inhibited the glycometabolism disorder in chondroctyes during osteoarthritis.

  作者：Xiong, Liwei. 杂志名称： Glycoconjugate Journal  IF：3

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• Lactate Facilitates Pancreatic Repair Following Acute Pancreatitis by Promoting Reparative Macrophage Polarization.

  作者：Jiang, Jing, et al. 杂志名称：Cellular and Molecular Gastroenterology and Hepatology IF：7

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• RHBDF1 deficiency suppresses melanoma glycolysis and enhances efficacy of immunotherapy by facilitating glucose-6-phosphate isomerase degradation …

  作者：L Wang, YY Song, Y Wang, XX Liu, YL Yin, ... 杂志名称： Journal of Cardiovascular Pharmacology IF：10

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• NCAPD3 is involved in papillary thyroid carcinoma proliferation, metastasis, and aerobic glycolytic pathway.

  作者：Zhang, Liubing, Aiping Peng, and Yue Qin. 杂志名称：Discover Oncology  IF：3

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• TNF‐α‐Induced KAT2A Impedes BMMSC Quiescence by Mediating Succinylation of the Mitophagy‐Related Protein VCP.

  作者：Su, Zepeng, et al. 杂志名称：Advanced Science IF：14

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• Calcium-mediated mitochondrial fission and mitophagy drive glycolysis to facilitate arterivirus proliferation.

  作者：Sun, Zhe, et al. 杂志名称： PLoS pathogens  IF：5

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• The S-depalmitoylase ABHD10 is essential for sperm mitochondrial sheath formation and male fertility

  作者：S Zhou, H Zhou, H Xu, M Xiong, S Gan, D Liu, ... 杂志名称：Acta Pharmacol Sin IF：16

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• Exosomes from PYCR1 knockdown bone marrow mesenchymal stem inhibits aerobic glycolysis and the growth of bladder cancer cells via regulation of the …

  作者：Z Li, Y Jiang, J Liu, H Fu, Q Yang, ... 杂志名称：Antioxidants IF：5

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• DRAM1 enhances the proliferation and metastasis of gastric cancer through the PI3K/AKT/mTOR signaling pathway and energy metabolism.

  作者：Wu, Xinrong, et al. 杂志名称：Scientific Reports IF：4

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• Gap junctions mediate glucose transfer to promote colon cancer growth in three-dimensional spheroid culture

  作者：K Gong, Q Hong, H Wu, F Wang, L Zhong, L Shen, ... 杂志名称：Microbiology Spectrum IF：10

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• Hypoxia promotes histone H3K9 lactylation to enhance LAMC2 transcription in esophageal squamous cell carcinoma.

  作者：Zang, Yong, et al. 杂志名称：Iscience IF：5

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• Porcine reproductive and respiratory syndrome virus-mediated lactate facilitates virus replication by targeting MAVS

  作者：L Zhang, X Liu, J Mao, Y Sun, Y Gao, J Bai, ... 杂志名称：Br J Nutr IF：3

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• Vitamin D-VDR (vitamin D receptor) alleviates glucose metabolism reprogramming in lipopolysaccharide-induced acute kidney injury

  作者：Q Dai, H Zhang, S Tang, X Wu, J Wang, B Yi, ... 杂志名称：Biology IF：3

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• Low level of lactate and trophoblast dysfunction mediated by SNAI1/PDK1 contributes to miscarriage.

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• Cucurbitacin B from Cucurbitaceae Plants: Treating Pancreatic Cancer via Inducing Mitophagy, Inhibiting Glycolysis, and Enhancing Immune Function

  作者：D Yin, H Chen, X Jing, S Lin, Y Sun, R Chang, Y Feng, ... 杂志名称：Exp Neurol IF：5

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• Targeting macrophage polarization by inhibiting Pim2 alleviates inflammatory arthritis via metabolic reprogramming.

  作者：Xu, Xiaojun, et al. 杂志名称：Cellular & Molecular Immunology  IF：20

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• Glucose-induced LINC01419 reprograms the glycolytic pathway by recruiting YBX1 to enhance PDK1 mRNA stability in hepatocellular carcinoma

  作者：刘艳芳 杂志名称：Asian-Australasian Journal of Animal Sciences IF：8

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• CDCA3-MYC positive feedback loop promotes bladder cancer progression via ENO1-mediated glycolysis.

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• ARL5B Drives Esophageal Squamous Cell Carcinoma Progression via ROCK1–SREBP1‐Mediated Lipid Metabolic Reprogramming

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• Divalent Metal Cations Favor Bone Regeneration Through Promoting Aerobic Glycolysis of Differentiated Mscs and Modulating Activity of Sensory and Autonomic Nervous Systems.

  作者：Luo, Ying, et al. 杂志名称： IF：

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• Lactate administration induces skeletal muscle synthesis by influencing Akt/mTOR and MuRF1 in non‐trained mice but not in trained mice.

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